A sad day for the likes of Chief Keef, Lil Wayne and A$AP Rocky as Actavis, maker of the ‘Champagne of sizzurp’ announces plans to pull its Promethazine Codeine cough syrup from shelves for good.

While a host of artists have expressed a fondness for getting double-cupped, mixing the highly refined prescription medicine with Sprite, perhaps hardest hit will be poor Justin Bieber. It would seem that another shameless attempt to appropriate hip-hop culture has backfired on Bizzle, seeing many blame recent photos of him and his friends sipping syrup for the product’s withdrawal.

This actually seems to be compelling evidence that Bieber’s dalliance has been the straw that broke the camel’s back, as lean had been a widely advertised fixture in culture and music with no response from Actavis, long before the Vanilla Prince had a try.

Soulja Boy and Chief Keef regularly broadcast their usage, huge chunks of their Instagrams devoted to purple drank posts. 2 Chainz is facing felony drug possession charges after being caught with it in his luggage last June. DJ Screw’s death over 14 years ago has been attributed to a codeine overdose.

Previously hovering at around $800 for a pint-sized bottle, sustaining a habit may require some budget reshuffling for sizzurp’s famous poster boys – with one rapper reportedly offering to pay his dealer $100,000 for the same amount.

This might signal an interesting new career direction for Soulja Boy, who on Tuesday posted a photo of six bottles of Prometh with Codeine cough syrup to his Instagram with the caption, ‘Soulja got the juice. They say the streets dry, I say you gotta be kiddin’ me. I serve everybody.’